Small RNAs Are

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Master regulators of gene expression

Play critical roles in biological pathways. Mutations in small RNA genes drive disease.

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Required for stem cell differentiation

Make and maintain all of our tissues.
Each tissue has a unique ‘fingerprint’.
Small RNAs classify tissue better than other molecules.

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Good bioanalytical targets

Found in every tissue and fluid.
Easily extracted and very stable.
As few as 1 molecule can be detected.