Small RNAs Are
Master regulators of gene expression
Play critical roles in biological pathways. Mutations in small RNA genes drive disease.
Required for stem cell differentiation
Make and maintain all of our tissues.
Each tissue has a unique ‘fingerprint’.
Small RNAs classify tissue better than other molecules.
Good bioanalytical targets
Found in every tissue and fluid.
Easily extracted and very stable.
As few as 1 molecule can be detected.